Advanced Organic Chemistry, Part A: Structure and Mechanisms 5th Edition

Pdf Book Name: Advanced Organic Chemistry, Part A: Structure and Mechanisms 5th Edition
Author: Francis A. Carey, Richard J. Sundberg
Publisher: Springer
ISBN-10, 13: 9780387683461,978-0387683461
Year: 2008
Pages: 1199 pages
Language: English
File size: 55 MB
File format: PDF,EPUB

Advanced Organic Chemistry, Part A: Structure and Mechanisms 5th Edition Pdf Book Description:

This Fifth Edition marks the beginning of the fourth decade that Advanced Organic Chemistry has been available. As with the previous editions, the goal of this text is to allow students to build on the foundation of introductory organic chemistry and attain a level of knowledge and understanding that will permit them to comprehend much of the material that appears in the contemporary chemical literature. There have been major developments in organic chemistry in recent years, and these have had a major influence in shaping this new edition to make it more useful to students, instructors, and other readers. The expanding application of computational chemistry is reflected by amplified discussion of this area, especially density function theory (DFT) calculations in Chapter 1. Examples of computational studies are included in subsequent chapters that deal with specific structures, reactions and properties. Chapter 2 discusses the principles of both configuration and conformation, which were previously treated in two separate chapters. The current emphasis on enantioselectivity, including development of many enantioselective catalysts, prompted the expansion of the section on stereoselective reactions to include examples of enantioselective reactions. Chapter 3, which covers the application of thermodynamics and kinetics to organic chemistry, has been reorganized to place emphasis on structural effects on stability and reactivity. This chapter lays the groundwork for later chapters by considering stability effects on carbocations, carbanions, radicals, and carbonyl compounds.

The revision and updating of Advanced Organic Chemistry that appears as the Fifth Edition spanned the period September 2002 through December 2006. Each chapter was reworked and updated and some reorganization was done, as described in the Prefaces to Parts A and B. This period began at the point of conversion of library resources to electronic form. Our university library terminated paper subscriptions to the journals of the American Chemical Society and other journals that are available electronically as of the end of 2002. Shortly thereafter, an excavation mishap at an adjacent construction project led to structural damage and closure of our departmental library. It remained closed through June 2007, but thanks to the efforts of Carol Hunter, Beth Blanton-Kent, Christine Wiedman, Robert Burnett, and Wynne Stuart, I was able to maintain access to a few key print journals including the Journal of the American Chemical Society, Journal of Organic Chemistry, Organic Letters, Tetrahedron, and Tetrahedron Letters. These circumstances largely completed an evolution in the source for specific examples and data. In the earlier editions, these were primarily the result of direct print encounter or search of printed Chemical Abstracts indices. The current edition relies mainly on electronic keyword and structure searches. Neither the former nor the latter method is entirely systematic or comprehensive, so there is a considerable element of circumstance in the inclusion of specific material. There is no intent that specific examples reflect either priority of discovery or relative importance. Rather, they are interesting examples that illustrate the point in question