The comet assay in toxicology 2nd Edition

Book Name: The comet assay in toxicology 2nd Edition
Author: Diana Anderson, Diana Anderson, Alok Dhawan, Alok Dhawan, Andrew Collins, Michael Plewa, Tomas Gichner, Narendra Singh, Declan McKenna, Ashutosh Kumar, S Piperakis, Maria Dusinska, Emilio Rojas, Siegfried Knasmueller, Giada Frenzilli, Sheena Lewis, Andreas Hartmann, Mark Browne, D Lovell
Publisher: Royal Society of Chemistry
ISBN-10: 178262287X,978-1-78262-287-1,978-1-78262-289-5,1782622896,978-1-78262-915-3
Year: 2016
Pages: 590
Language: English
File size: 10 Mb
File format: PDF

The comet assay in toxicology 2nd Edition Pdf Book Description:

Concerns regarding the negative effects of compounds within the environment have produced a demand for better methods to estimate their possible effects on human health. 1 possible solution is the flexible and innovative Comet assay. Simple, sensitive, visual and rapid, this contemporary toxicological method allows qualitative and quantitative evaluation of DNA damage in cells. This assay is employed in diverse fields which range from clinical programs, human observation and ecological toxicology through to genetic toxicity testing.

This revised and updated edition of this Comet Assay in Toxicology supplies the most recent advice on this important instrument. It addresses, comprehensive, the various protocols, statistical investigations and software used worldwide. The book starts with a review of this genesis of this assay for all those new to the procedure and moves on to describe procedures followed to evaluate unique kinds of DNA damage, various uses of this assay, and instructions for the behavior of this assay in in vitro and in vivo systems. New chapters written with this variant will offer advice on the most modern approaches and programs, such as in silico approaches, on meta-analysis of information and about the use of this Comet Assay in nanotoxicology. This publication will serve as both a reference and a guide to students in Addition to researchers in the biomedical, pharmaceutical and biochemical sciences areas.